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HPG Axis Reactivation Science

Meaning

HPG Axis Reactivation Science is the specialized clinical and pharmacological discipline focused on stimulating and restoring the endogenous, self-sustained function of the Hypothalamic-Pituitary-Gonadal (HPG) axis. This science is primarily applied to individuals experiencing secondary hypogonadism or gonadal suppression following exogenous hormone administration. The objective is to encourage the body’s natural production of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and the subsequent gonadal sex hormones, thereby re-establishing long-term hormonal homeostasis without continuous external intervention.