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HPG Axis Genetic Control

Meaning

HPG Axis Genetic Control refers to the influence of inherited gene variants on the structure, function, and regulatory feedback loops of the Hypothalamic-Pituitary-Gonadal (HPG) axis. This genetic influence dictates an individual’s baseline production, signaling efficiency, and metabolism of key sex hormones, including testosterone and estrogen. Variations in genes coding for hormone receptors or regulatory enzymes can significantly impact reproductive health, libido, bone density, and muscle maintenance throughout the lifespan. A comprehensive understanding of this control mechanism is vital for effective hormonal optimization.