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HPG Axis Function Testing

Meaning

HPG Axis Function Testing is a specialized clinical assessment designed to comprehensively evaluate the integrity, responsiveness, and functional reserve of the Hypothalamic-Pituitary-Gonadal axis. This axis is the central neuroendocrine regulator of reproductive and sexual hormones, including testosterone and estrogen. The testing process involves measuring key trophic hormones and downstream sex steroids, often utilizing provocative stimuli to assess the system’s capacity for secretion. The resulting profile is vital for diagnosing the etiology of hormonal deficiencies and tailoring precise hormone optimization protocols.