Skip to main content

Hormone Timing Dependency

Meaning

Hormone Timing Dependency is a clinical principle asserting that the therapeutic efficacy and safety profile of exogenous hormone administration are significantly influenced by the chronological age of the patient and the duration since the onset of hormone deficiency. This dependency suggests that initiating hormone replacement within a specific, critical “window of opportunity” may yield superior outcomes compared to starting therapy many years after endocrine decline has become established. This concept is particularly relevant in perimenopause and postmenopause.