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Hormone Replacement Scheduling

Meaning

Hormone Replacement Scheduling is the clinical strategy of determining the precise timing, frequency, and dose of exogenous hormone administration to best replicate the body’s natural, often pulsatile and circadian, endocrine rhythms. This advanced approach moves significantly beyond static, once-daily dosing to optimize the therapeutic window and minimize the risk of receptor desensitization or negative feedback loop suppression. Optimal scheduling aims to restore not just hormone levels but also the vital kinetics of hormonal signaling. This is essential for maximizing clinical benefit and supporting long-term health.