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Hormone Receptor Genes

Meaning

Hormone Receptor Genes are the specific segments of DNA that contain the blueprint for manufacturing the protein receptors to which hormones bind. These receptors are the molecular switches that translate the hormone’s message into a cellular action, acting as ligand-activated transcription factors. Genetic variations, or polymorphisms, within these genes can alter the structure or quantity of the receptor, directly impacting a tissue’s sensitivity to a circulating hormone. Assessing these genes can provide predictive insight into an individual’s response to both endogenous and therapeutic hormones.