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Hormone Receptor Expression

Meaning

Hormone Receptor Expression describes the process by which cells synthesize and present specific receptor proteins, either on their surface or within the cytoplasm and nucleus, that are capable of binding to circulating hormones. The level and type of receptor expression fundamentally determine a target cell’s sensitivity and responsiveness to a particular hormone, acting as the critical molecular link between the endocrine signal and the resulting physiological effect. Clinical assessment of receptor expression is essential in personalized medicine, particularly in hormone-sensitive cancers.