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Hormone Pulsatility Restoration

Meaning

Hormone Pulsatility Restoration is a therapeutic strategy focused on re-establishing the natural, rhythmic, and intermittent secretion patterns of key endocrine hormones, particularly those governed by the hypothalamic-pituitary axis, such as Growth Hormone (GH) and Gonadotropins. Many hormones are not released in a steady stream but in distinct, timed pulses, and the amplitude and frequency of these pulses are critical for optimal biological signaling. The goal of restoration is to correct the flattened or erratic secretion profiles often observed with age or chronic dysfunction, thereby maximizing the hormone’s physiological effectiveness and minimizing side effects.