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Hormone-Metabolism Interface

Meaning

The Hormone-Metabolism Interface is the complex, bidirectional signaling network where the endocrine system directly regulates and is regulated by the body’s metabolic processes, including energy expenditure, nutrient storage, and substrate utilization. This interface encompasses the actions of key hormones like insulin, thyroid hormone, cortisol, and sex steroids on cellular metabolism, as well as the metabolic feedback loops that influence hormone secretion. Understanding this critical junction is essential for addressing conditions such as insulin resistance, obesity, and thyroid dysfunction. It represents a fundamental principle of integrated human physiology.