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Hormone Metabolism Enzymes

Meaning

Hormone metabolism enzymes are a specialized group of proteins, primarily located in the liver, gut, and target tissues, responsible for the synthesis, activation, and inactivation of steroid and peptide hormones. These enzymatic pathways precisely control the circulating levels and biological activity of hormones like testosterone, estrogen, cortisol, and thyroid hormone. Their function is crucial for maintaining endocrine balance and adapting hormone signaling in response to physiological demands. Genetic variations or external factors influencing these enzymes can profoundly alter hormonal status and health outcomes.