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Hormone-Mediated Mood Stability

Meaning

Hormone-Mediated Mood Stability describes the direct and indirect influence of the endocrine system on maintaining a balanced and resilient emotional state, characterized by consistent energy levels and a reduced susceptibility to mood fluctuations. Key steroid hormones, including estrogen, progesterone, and testosterone, act as potent neuromodulators, influencing neurotransmitter synthesis, receptor density, and neuronal plasticity within the limbic system and prefrontal cortex. Declines or imbalances in these hormones, such as during perimenopause or androgen deficiency, frequently correlate with clinical presentations of anxiety, irritability, or depressed mood. Restoration of a youthful, balanced hormonal profile is often a foundational step in addressing complex mood disorders.