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Hormone Feedback Loops

Meaning

Hormone feedback loops are the core regulatory mechanisms within the endocrine system, where the output of a pathway acts to modulate its own production, ensuring precise control over circulating hormone concentrations. These loops are categorized as negative, where the end product inhibits upstream release, or positive, where the end product stimulates further release. Maintaining the sensitivity and responsiveness of these loops is essential for preventing both hormone deficiency and excess, thereby preserving systemic homeostasis.