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Hormone Binding Globulin Management

Meaning

Hormone Binding Globulin Management involves the clinical strategies aimed at optimizing the levels and functional activity of transport proteins like Sex Hormone Binding Globulin (SHBG) and Thyroid Binding Globulin (TBG). These proteins dictate the availability of free, biologically active hormones circulating to target tissues. Effective management ensures that total hormone measurements accurately reflect the free fraction available for receptor interaction. Balancing these carriers is essential for achieving eugonadal or euthyroid states.