Hormone Balance describes a state of optimal endocrine function where the concentrations and activities of various systemic hormones—steroids, peptides, and amines—are synchronized to support physiological homeostasis and well-being. This is not a static level but a dynamic equilibrium maintained through precise feedback regulation. Imbalances disrupt cellular signaling, impacting metabolism, mood, and vitality.
Origin
This term originates from the historical understanding of endocrinology, emphasizing the humoral theory where bodily fluids, including hormones, must remain in proper proportion for health. It is a holistic concept rooted in maintaining internal equilibrium.
Mechanism
Achieving balance relies on the functional integrity of the entire neuroendocrine axis, from the hypothalamus to the target tissues. This involves appropriate synthesis, secretion, transport via binding globulins, receptor affinity, and subsequent metabolic clearance of hormones. Interventions aim to restore sensitivity at the receptor level or provide physiologic replacement to support the body’s inherent regulatory capacity.
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