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Hormonal Window Adherence

Meaning

Hormonal Window Adherence is the critical clinical practice of strictly timing the administration of hormonal agents or modulators to coincide precisely with the body’s natural, optimal physiological periods for absorption, utilization, or synergistic effect. This principle is founded on the understanding that the efficacy and safety of hormonal therapies are significantly enhanced when delivered in accordance with the body’s inherent circadian and ultradian rhythms. Non-adherence to these specific windows can substantially diminish therapeutic benefit and potentially increase the risk of adverse effects by disrupting natural, finely tuned endocrine feedback loops.