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Hormonal Threshold Identification

Meaning

Hormonal Threshold Identification is the precise clinical process of determining the minimal effective concentration of a specific hormone required to elicit a desired physiological or therapeutic response in an individual. This concept acknowledges that the optimal hormone level is highly personalized and often lies within a narrow, non-population-average window, not simply within the broad reference range. Accurate identification prevents the risks associated with both sub-therapeutic dosing and supraphysiological excess, ensuring patient safety. This is a critical step in personalized endocrine therapy to maximize benefit and minimize side effects.