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Hormonal Substrate Superiority

Meaning

Hormonal Substrate Superiority describes a condition where the available precursor molecules, or substrates, are present in optimal quantities and quality to support robust and efficient endogenous hormone synthesis. When this superiority exists, the endocrine glands, such as the adrenals or gonads, can efficiently convert raw materials into functional signaling molecules without metabolic bottleneck. This concept moves beyond simple deficiency to evaluate the quality of the building blocks available for endocrine function.