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Hormonal Status Biomarkers

Meaning

Hormonal Status Biomarkers are quantifiable biological indicators—such as specific hormone concentrations, their metabolites, or the proteins that regulate their action—that reflect the current state and function of an individual’s endocrine system. These markers move beyond simple reference ranges to provide a functional assessment of glandular output, receptor sensitivity, and metabolic clearance pathways. Examples include the free fractions of sex steroids, the cortisol-to-DHEA ratio, and thyroid hormone T3 uptake. Clinically, they serve as objective metrics to diagnose imbalances, monitor therapeutic efficacy, and predict future health risks.