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Hormonal Signal Strength

Meaning

Hormonal Signal Strength refers to the overall integrated magnitude of an endocrine message perceived by target tissues, encompassing both circulating hormone concentration and the functional status of the corresponding receptor apparatus. It is a composite metric assessing not just the amount of hormone present, but the resulting biological effect achieved at the cellular interface. Low signal strength can result from low ligand concentration, receptor downregulation, or downstream signaling impairment, even if the hormone level appears adequate on a standard assay. Optimizing this strength is the ultimate goal of endocrine modulation.