Hormonal Set-Point Restoration is the clinical goal of returning specific circulating hormone concentrations to their genetically or developmentally predetermined optimal reference ranges.
Origin
The idea of a ‘set-point’ is borrowed from thermostat regulation, applied here to endocrine feedback systems that drift due to aging or environmental factors.
Mechanism
Restoration often involves targeted modulation of upstream endocrine glands or the careful introduction of bioidentical hormone support to recalibrate the negative feedback loops.
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