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Hormonal Potency

Meaning

Hormonal Potency refers to the measure of a hormone’s intrinsic biological activity and the concentration required to elicit a specific magnitude of physiological response in a target tissue. This metric is a key pharmacological concept, quantifying the hormone’s affinity for its receptor, its half-life in circulation, and the efficiency of the subsequent intracellular signaling cascade. Clinically, understanding the relative potency of various endogenous hormones and their synthetic analogs is crucial for precise therapeutic dosing and predicting biological effect. A hormone with high potency requires a smaller dose to achieve the desired clinical outcome.