Skip to main content

Hormonal Lipolysis Regulation

Meaning

Hormonal lipolysis regulation is the precise control mechanism exerted by the endocrine system over the breakdown of triglycerides stored within adipocytes into glycerol and free fatty acids. This regulatory process is a dynamic, minute-to-minute balancing act, governed by the opposing actions of various hormones that either promote or inhibit fat breakdown. Maintaining appropriate regulation is essential for providing energy substrates to other tissues during fasting or exercise while preventing excessive or inappropriate fat mobilization. Dysfunction in this regulatory system is a central feature of dyslipidemia and insulin resistance.