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Hormonal Gradient Recalibration

Meaning

Hormonal gradient recalibration is a clinical and physiological process focused on restoring the optimal concentration differences, or gradients, of key hormones across various physiological compartments or cellular membranes. This involves normalizing the delicate balance between active hormones, their precursors, and their metabolites, as well as the sensitivity of their respective receptors. Effective recalibration is essential for restoring intercellular communication and ensuring that target tissues respond appropriately to endocrine signals. The goal is to move the endocrine system from a state of dysregulation back to a state of dynamic equilibrium.