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Hormonal Fraction Analysis

Meaning

Hormonal Fraction Analysis is the detailed laboratory evaluation that separates total circulating hormones into their distinct biologically active and inactive components, such as free versus bound testosterone or estrogen. This quantification is vital because only the unbound, free fraction is generally available to interact with target tissue receptors and exert physiological effects. Relying solely on total hormone levels can mask underlying issues like altered Sex Hormone Binding Globulin (SHBG) capacity or protein displacement. Accurate fraction analysis provides the true picture of hormonal signaling potential.