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Hormonal Feedback Modulation

Meaning

Hormonal Feedback Modulation is the clinical and physiological process of deliberately adjusting the complex, self-regulating loops within the endocrine system to achieve a desired therapeutic outcome or restore homeostatic balance. The endocrine system operates through negative and positive feedback loops where the output of one gland controls the input to another, ensuring hormone levels remain within a tight physiological range. Effective modulation requires a deep understanding of these axes, such as the Hypothalamic-Pituitary-Adrenal (HPA) or Gonadal (HPG) systems. This precise adjustment is essential for individualized hormonal therapy.