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Hormonal Feedback Loop

Meaning

A hormonal feedback loop is a fundamental regulatory mechanism within the endocrine system where the output of a pathway, typically a secreted hormone, influences its own production rate. These loops are essential for maintaining physiological homeostasis by ensuring hormone concentrations remain within a narrow, non-toxic, and functional range. The loop can be negative, inhibiting further release when levels are high, or positive, stimulating further release for a specific physiological event. Understanding these loops is paramount for effective endocrine management and therapy.