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Hormonal Feedback Inhibition

Meaning

Hormonal Feedback Inhibition is a core principle of endocrinology describing the regulatory process where the circulating level of a hormone, or the effect it produces, acts to suppress the further release of its own stimulating hormone from the pituitary or hypothalamus. This negative feedback loop is crucial for preventing hormonal overproduction and maintaining precise, dynamic equilibrium within the hypothalamic-pituitary-target gland axes. It is a fundamental mechanism of endocrine self-regulation.