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Hormonal Decline Cognitive Impact

Meaning

Hormonal Decline Cognitive Impact refers to the measurable negative effects on neurocognitive functions, such as memory, executive function, and processing speed, that are directly attributable to the age-related reduction or dysregulation of key endocrine hormones. The decline of sex steroids like estrogen and testosterone, and neurosteroids like DHEA, significantly impacts neuronal health, synaptic plasticity, and cerebral blood flow. Clinically, recognizing this impact is essential for implementing targeted hormone replacement or modulatory therapies to preserve brain health and function.