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Hormonal Decline

Meaning

Hormonal decline describes the physiological reduction in the production, circulating levels, or biological effectiveness of key endocrine hormones that typically occurs with advancing age. This process, often gradual, can lead to symptomatic changes in energy, mood, body composition, and sexual function. Clinically, this is most commonly observed as andropause (testosterone decline) in men and perimenopause/menopause (estrogen/progesterone decline) in women. The resulting endocrine shifts contribute significantly to the aging phenotype and diminished wellness.