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Hormonal Command System

Meaning

The Hormonal Command System is a conceptual, clinical term used to describe the integrated, hierarchical network of endocrine glands and regulatory centers that orchestrate systemic physiological function. This system is primarily anchored by the Hypothalamic-Pituitary-Adrenal (HPA) and Hypothalamic-Pituitary-Gonadal (HPG) axes, which together govern stress response, metabolism, growth, and reproduction. Its optimal function is non-negotiable for maintaining homeostasis, vitality, and longevity. When the command system is compromised, a cascade of dysregulation impacts multiple organ systems.