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Hormonal Axis Resetting

Meaning

Hormonal Axis Resetting is a clinical strategy aimed at restoring the optimal function and feedback sensitivity of a major endocrine regulatory system, such as the Hypothalamic-Pituitary-Adrenal (HPA) or Hypothalamic-Pituitary-Gonadal (HPG) axis. This goes beyond simple hormone replacement by focusing on the central command centers—the hypothalamus and pituitary—to re-establish a healthy, rhythmic, and responsive hormonal output. The goal is to move the body away from a state of chronic dysregulation, often seen with prolonged stress or aging, toward a state of balanced, endogenous hormone production. This is a restorative, not merely suppressive, therapeutic objective.