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HOMA IR Score Improvement

Meaning

HOMA IR Score Improvement refers to the clinical objective of lowering the calculated Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) value, which is a widely used surrogate marker for estimating insulin resistance and pancreatic beta-cell function. A lower HOMA-IR score signifies enhanced insulin sensitivity, indicating that the body’s cells are responding more efficiently to circulating insulin, thereby requiring less insulin to maintain normal blood glucose levels. Improvement in this score is a direct clinical marker of better metabolic health, reduced risk for Type 2 diabetes, and optimized hormonal signaling. This metric is a key indicator in longevity and metabolic optimization protocols.