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HOMA-IR Management

Meaning

HOMA-IR Management is the clinical strategy focused on reducing an elevated Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) score, a calculated index used to quantify insulin resistance and beta-cell function. A high HOMA-IR score indicates that the body’s cells are less responsive to insulin, necessitating a greater output of the hormone to maintain euglycemia, a precursor to metabolic syndrome and type 2 diabetes. Management protocols are highly personalized, integrating nutritional modification, exercise prescription, and targeted pharmaceutical or nutraceutical interventions to improve insulin sensitivity and protect pancreatic function. Successfully managing HOMA-IR is paramount for hormonal balance and cardiovascular health.