Skip to main content

HLA-B 57: 01

Meaning

HLA-B 57: 01 is a specific allele, or variant, of the Human Leukocyte Antigen B gene, which serves as a critical pharmacogenetic marker in clinical practice. The presence of this allele indicates a significantly elevated risk of developing a severe, potentially life-threatening hypersensitivity reaction to certain medications, most notably the antiretroviral drug abacavir used in HIV treatment. Universal screening for this allele is mandated before initiating therapy with the associated drug.