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Hippocampus Atrophy

Meaning

Hippocampus Atrophy refers to the pathological and measurable reduction in the overall volume and size of the hippocampus, a critical bilateral structure deep within the brain’s temporal lobe that is absolutely essential for explicit memory consolidation and spatial navigation. This structural change is frequently observed clinically in chronic conditions associated with prolonged, unmanaged stress, major depressive disorder, and specific neurodegenerative diseases like Alzheimer’s disease. It serves as a tangible physical manifestation of prolonged neurotoxicity and impaired neurogenesis.