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Hippocampal Volume Maintenance

Meaning

The clinical and biological strategy focused on preserving the structural size and functional integrity of the hippocampus, a critical brain region central to memory formation, spatial navigation, and emotional regulation. Volume loss in this area is a well-established neurobiological marker of chronic stress, aging, and neurodegenerative processes, often linked to prolonged exposure to elevated cortisol levels. Maintenance efforts aim to counteract atrophy and support ongoing neurogenesis, thereby sustaining cognitive health and stress resilience.