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Hippocampal-Neocortical Dialogue

Meaning

The Hippocampal-Neocortical Dialogue is the critical, bidirectional exchange of information between the hippocampus, the brain structure essential for forming new declarative memories, and the neocortex, the site of long-term memory storage and complex cognition. This dialogue is particularly active during specific phases of sleep, where it facilitates the consolidation of recent learning into durable, integrated knowledge structures. Disruption of this communication impairs learning and memory stabilization.