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High-Target Ranges

Meaning

High-Target Ranges refer to a personalized, proactive clinical strategy where a patient’s biomarker levels, particularly circulating hormones, are intentionally maintained at the upper end of the established laboratory reference interval or even slightly above it, provided this is clinically safe and justified. This specific approach is often utilized in the context of age-related hormonal decline, with the goal of restoring the physiological vigor and optimal function typically associated with a more youthful endocrine profile, rather than merely avoiding a frank deficiency state. This nuanced decision requires careful clinical justification based on patient symptoms, comprehensive risk profile, and clearly defined therapeutic goals.