What is the Origin of High-Resolution Diagnostics?

This concept stems from advancements in mass spectrometry and highly sensitive immunoassay technology, allowing for the detection of analytes in the picomolar range. The term implies a significant leap in analytical precision compared to older methodologies. It champions the view that subclinical deviations are clinically relevant deviations.

What is the Mechanism of High-Resolution Diagnostics?

The operational mechanism involves identifying minute shifts in the equilibrium of hormone production, transport, or clearance before they manifest as overt clinical symptoms. For example, measuring ultra-low levels of cortisol metabolites can reveal subtle adrenal fatigue patterns not apparent in total cortisol readings. This granular data informs preemptive modulation of the entire endocrine feedback loop, optimizing function at the earliest detectable stage.

High-Resolution Diagnostics

Meaning

An advanced diagnostic approach utilizing highly sensitive assays capable of measuring biomarkers, including hormones and metabolites, at concentrations far below standard clinical reference limits. This provides an exceptionally detailed profile of physiological function, revealing subtle imbalances often missed by conventional testing. We seek to map the endocrine landscape with near-cellular specificity. Such resolution allows for truly personalized therapeutic targets.