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High-Output System

Meaning

A High-Output System, in the context of human physiology, describes a physiological circuit, often cardiovascular or endocrine, characterized by an elevated rate of activity, production, or throughput required to meet intense metabolic or homeostatic demands. In endocrinology, this might refer to an adrenal gland under sustained stress producing supra-normal levels of glucocorticoids or a thyroid axis operating at maximal capacity to maintain euthyroidism during critical illness. Such a state implies significant resource allocation to maintain systemic equilibrium.