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High-Normal Reference Targets

Meaning

High-Normal Reference Targets are a clinical philosophy and set of biomarker goals that aim to maintain key physiological and hormonal values at the upper end of the established laboratory reference range for healthy young adults. This approach recognizes that standard population reference ranges often reflect a mean that includes sub-optimal levels and age-related decline. Targeting the high-normal range, particularly for crucial hormones like free testosterone, DHEA, and Vitamin D, is a proactive strategy intended to optimize systemic function, vitality, and resilience, rather than simply avoiding overt deficiency. It represents a significant clinical shift from disease-avoidance to proactive health-optimization.