The acute and chronic physiological adaptations induced by engaging in High-Intensity Interval Training (HIIT), a form of exercise characterized by short bursts of near-maximal effort followed by brief recovery periods. This response includes significant improvements in cardiorespiratory fitness, enhanced insulin sensitivity, and favorable changes in the anabolic hormone profile. It is a powerful stimulus for metabolic remodeling.
Origin
This concept originates from exercise physiology, evolving from research into anaerobic and aerobic conditioning methods. The term ‘Response’ emphasizes the body’s robust and systemic reaction to this specific training modality. HIIT gained prominence for its time-efficient ability to elicit adaptations traditionally associated with much longer, steady-state exercise.
Mechanism
The immediate mechanism involves rapidly depleting intramuscular glycogen stores and creating a significant oxygen deficit, triggering a potent release of catecholamines and growth hormone. Chronically, this stress upregulates the expression of PGC-1alpha, a master regulator of mitochondrial biogenesis, leading to increased aerobic capacity and improved fat oxidation. The resulting enhanced glucose uptake also drives systemic insulin sensitivity.
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