High-Intensity Exercise Neurology investigates the acute and chronic effects of maximal physical exertion on central nervous system function, including neurogenesis and neurotransmitter balance. We examine how this stressor modulates the release of neurotrophic factors essential for cognitive maintenance and mood regulation. This field connects systemic physiological stress to immediate and long-term brain adaptation. It is the study of exercise as a potent neurological stimulus.
Origin
The term merges the established fields of exercise physiology (high-intensity interval training) and neuroscience. Its rise reflects growing evidence that physical exertion profoundly impacts brain structure and function beyond cardiovascular benefits. We apply this to understand the neuroendocrine cascade initiated by intense effort. The neurology component emphasizes central adaptation.
Mechanism
Intense exercise rapidly elevates systemic factors, including BDNF and various circulating myokines, which cross the blood-brain barrier to influence neuronal health. Furthermore, the acute surge in catecholamines sets the stage for subsequent homeostatic adjustments in receptor sensitivity. This powerful stimulus drives mitochondrial adaptation within neurons and can promote synaptic pruning, leading to a more resilient and efficient neural architecture. Cortisol spikes must be managed to ensure the net effect remains neurotrophic.
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