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High-Dose Supplementation

Meaning

High-Dose Supplementation is a specialized clinical strategy involving the precise administration of micronutrients, essential vitamins, or specific non-hormonal bioactive compounds at concentrations significantly exceeding the Recommended Dietary Allowance (RDA) or typical maintenance levels. This targeted approach is deliberately employed to achieve a specific pharmacological or supraphysiological effect, often to rapidly correct profound, long-standing deficiencies, robustly support intensive metabolic pathways, or exert a powerful therapeutic action beyond basic nutritional support. It requires careful clinical oversight due to the increased potential for pharmacological effects.