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High-Amplitude LH Pulses

Meaning

High-Amplitude LH Pulses refer to the release of Luteinizing Hormone (LH) from the anterior pituitary gland in a pattern characterized by infrequent but significantly large, robust bursts of hormone concentration into the bloodstream. This specific pulsatile release pattern is a critical physiological signal, particularly in males, as it drives the Leydig cells in the testes to synthesize and secrete testosterone. The amplitude, or magnitude, of these pulses is a key determinant of testicular steroidogenesis and is closely monitored in the clinical assessment of reproductive and overall endocrine function. Optimizing the amplitude and frequency of these pulses is often a therapeutic goal in managing hypogonadism.