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Heart Valve Disease

Meaning

Heart valve disease is a pathological clinical condition characterized by structural damage or functional malfunction of one or more of the four critical cardiac valves—aortic, mitral, tricuspid, or pulmonary—leading to severely impaired blood flow dynamics. This malfunction typically manifests as either stenosis, a narrowing that pathologically impedes forward blood flow, or regurgitation, a leakage that allows abnormal backward flow. In the hormonal health context, certain endocrine imbalances or specific therapeutic agents can secondarily influence the risk or accelerate the progression of this significant cardiovascular pathology.