Healthspan is defined as the period of life spent in good health, free from the chronic diseases and disabilities associated with advanced age. It is a measure distinct from mere lifespan, focusing instead on the quality and functional capacity of those years. Optimizing healthspan is a primary objective in contemporary longevity science and preventative endocrinology.
Origin
The concept arose as researchers recognized that extending chronological life without maintaining function provided limited benefit. It represents a philosophical shift in aging research towards prioritizing physiological vigor over simple longevity statistics.
Mechanism
Enhancing healthspan involves maintaining anabolic signaling, preserving muscle mass through resistance training, and optimizing hormonal milieu, particularly growth hormone and sex steroids. Cellular resilience, supported by mitigating oxidative stress and improving mitochondrial function, directly contributes to maintaining functional capacity over time. Effective healthspan extension requires systemic physiological recalibration.
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