What is the Origin of Healthspan Metrics?

The term originates from longevity research, contrasting the concept of life duration with the quality of life experienced throughout that duration. It emphasizes the functional output of biological systems rather than just their structural presence. It provides a tangible target for anti-aging and regenerative strategies.

What is the Mechanism of Healthspan Metrics?

Optimization of Healthspan Metrics relies on maintaining robust hormonal signaling, particularly concerning anabolic hormones like IGF-1 and sex steroids, within optimal ranges. Monitoring these metrics allows us to track the efficacy of interventions designed to slow molecular aging processes. Successful mitigation of chronic inflammation, often driven by metabolic dysfunction, directly improves these measurable outcomes.

Healthspan Metrics

Meaning

Healthspan Metrics are objective, quantifiable measures used to assess the duration of life spent in optimal physiological function, distinct from mere lifespan. These markers often include assessments of cardiovascular fitness, cognitive acuity, and the functional status of key endocrine axes. Our goal is to shift the clinical focus from extending years to maximizing functional vitality within those years.