A comprehensive, proactive clinical plan designed to maximize the duration of an individual’s life spent in a state of optimal physical and cognitive function, distinct from mere lifespan extension. This strategy heavily incorporates optimization of endocrine function, metabolic efficiency, and cellular repair mechanisms. We target the root causes of age-associated functional decline.
Origin
This term is rooted in the field of geroscience, shifting the clinical focus from treating pathology to proactively preserving wellness across the lifespan. Extension implies a deliberate effort to slow the rate of biological aging processes. Strategy denotes a multi-faceted, long-term commitment to physiological optimization.
Mechanism
The strategy operates by addressing multiple hallmarks of aging simultaneously, often focusing on improving mitochondrial respiration efficiency and enhancing systemic signal fidelity. Key components include optimizing anabolic drive, managing chronic low-grade inflammation indicated by markers like hs-CRP, and ensuring robust cellular stress resistance. Through these interconnected biochemical improvements, the goal is to compress the period of morbidity at the end of life.
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