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Gut Microbiome Endocrine Axis

Meaning

The Gut Microbiome Endocrine Axis is a complex, bidirectional signaling network that links the vast community of microorganisms inhabiting the gastrointestinal tract with the host’s systemic endocrine system. This critical axis illustrates how metabolites and signals originating from the gut microbiota can profoundly influence the synthesis, circulating levels, and biological action of various hormones, including those regulating metabolism, appetite, stress response, and reproductive health. A thorough understanding of this intricate interplay is increasingly essential for clinical strategies in metabolic and hormonal wellness.